Oriheal Pimotone Plus 10mg (Pimobendan & Benazepril) Tablet for Dogs and Cats
Inclusive of all taxes
Product Details
| Product type | Oral Tablets |
| Volume / Quantity | Pack of 10 Tablets (or as presented in multi-strip boxes under Rx rules) |
| Target Species | Canines and Felines (Dogs and cats diagnosed with advanced cardiovascular disease, valvular insufficiency, or cardiac enlargement) |
| Common Use Case | Long-term therapeutic management of clinical congestive heart failure (CHF) stemming from Myxomatous Mitral Valve Disease (MMVD) or Dilated Cardiomyopathy (DCM); reduction of peripheral and systemic blood vessel congestion; delaying heart failure progression in pre-clinical DCM or mitral valve disease; and managing blood pressure to alleviate fatigue, chronic coughing, and exercise intolerance. |
Oriheal Pimotone Plus 10mg is an advanced, prescription-only dual-action veterinary cardiovascular medication meticulously formulated to manage clinical congestive heart failure (CHF) and structural heart diseases in dogs and cats. This high-potency formula delivers a synergistic fixed-dose combination of Pimobendan (10mg) and Benazepril Hydrochloride (20mg) designed to decrease cardiac workload and improve life expectancy in pets suffering from advanced heart conditions.
Pimobendan functions as a premier "inodilator" by acting as a calcium sensitizer to directly increase myocardial contractility (positive inotropy) while selectively inhibiting the phosphodiesterase III (PDE3) enzyme to dilate blood vessels without significantly raising heart tissue oxygen demand. Working alongside it, Benazepril Hydrochloride operates as a potent Angiotensin-Converting Enzyme (ACE) inhibitor that suppresses the renin-angiotensin-aldosterone system (RAAS), preventing the conversion of angiotensin I to angiotensin II to relax blood vessels and lower systemic blood pressure. Together, this dual mechanism aggressively counteracts conditions like Myxomatous Mitral Valve Disease (MMVD) and Dilated Cardiomyopathy (DCM), easing fluid buildup (pulmonary edema) and noticeably lessening severe clinical symptoms like coughing, breathlessness, and extreme lethargy.